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用5分钟了解NanoBRET™ Target Engagement Assay 药物 : 靶标相互作用细胞学检测技术

简介

NanoBRET™ TE 是Promega药物研发的金牌技术之一，可以在活细胞水平实时检测小分子化合物与靶点之间的亲和力和占有率，目前已经可以提供多种靶点相关的检测试剂盒，包括大于350种激酶、BET/BRD、HDAC、E3 Ligases、 NLRP3、PARP、GPCR和HSP等靶点。

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Short Videos

5分钟技术短视频

用5分钟了解NanoBRET™ Target Engagement Assay 药物 : 靶标相互作用细胞学检测技术

NanoBRET®Target Engagement K192 Kinase Selectivity System

NanoBRET®Target Engagement CDK Selectivity Systems

CCND1 Expression Vector

CCND3 Expression Vector

CCNE1 Expression Vector

CCNH Expression Vector

CCNK Expression Vector

CCNL2 Expression Vector

CCNT1 Expression Vector

CCNY Expression Vector

CDK10-NanoLuc® Fusion Vector

CDK14-NanoLuc® Fusion Vector

CDK16-NanoLuc® Fusion Vector

CDK17-NanoLuc® Fusion Vector

CDK18-NanoLuc® Fusion Vector

CDK1-NanoLuc® Fusion Vector

CDK2-NanoLuc® Fusion Vector

CDK3-NanoLuc® Fusion Vector

CDK5R1 Expression Vector

CDK5R2 Expression Vector

CHEK2-NanoLuc® Fusion Vector

CSNK2A1-NanoLuc® Fusion Vector

DCLK3-NanoLuc® Fusion Vector

DDR2(N456S)-NanoLuc® Fusion Vector

DYRK2-NanoLuc® Fusion Vector

EPHA3-NanoLuc® Fusion Vector

EPHB1-NanoLuc® Fusion Vector

ERN2-NanoLuc® Fusion Vector

FES-NanoLuc® Fusion Vector

FGFR3(G697C)-NanoLuc® Fusion Vector

FLT1-NanoLuc® Fusion Vector

FLT3(D835H)-NanoLuc® Fusion Vector

FLT3(D835V)-NanoLuc® Fusion Vector

FLT3(D835Y)-NanoLuc® Fusion Vector

FLT3(K663Q)-NanoLuc® Fusion Vector

FLT3(N841I)-NanoLuc® Fusion Vector

FLT3(R834Q)-NanoLuc® Fusion Vector

FYN(Y531F)-NanoLuc® Fusion Vector

HCK-NanoLuc® Fusion Vector

IGF1R-NanoLuc® Fusion Vector

INSR-NanoLuc® Fusion Vector

Intracellular TE Nano-Glo® Substrate/Inhibitor

JAK2(V617F)-NanoLuc® Fusion Vector

JAK2-NanoLuc® Fusion Vector

KIT(A829P)-NanoLuc® Fusion Vector

KIT(D816H)-NanoLuc® Fusion Vector

KIT(D816V)-NanoLuc® Fusion Vector

KIT(L576P)-NanoLuc® Fusion Vector

KIT(V559D)-NanoLuc® Fusion Vector

KIT(V559D,T670I)-NanoLuc® Fusion Vector

KIT(V559D,V654A)-NanoLuc® Fusion Vector

LIMK1-NanoLuc® Fusion Vector

LRRK2(G2019S)-NanoLuc® Fusion Vector

LRRK2(I2020T)-NanoLuc® Fusion Vector

LRRK2(R1441C)-NanoLuc® Fusion Vector

LRRK2-NanoLuc® Fusion Vector

MAP2K6-NanoLuc® Fusion Vector

MAP3K19-NanoLuc® Fusion Vector

MAP3K2-NanoLuc® Fusion Vector

MAP3K3-NanoLuc® Fusion Vector

MAP4K5-NanoLuc® Fusion Vector

MAPK14(T106M)-NanoLuc® Fusion Vector

MERTK(A708S)-NanoLuc® Fusion Vector

MERTK-NanoLuc® Fusion Vector

MET(D1228H)-NanoLuc® Fusion Vector

MET(D1228N)-NanoLuc® Fusion Vector

MET(F1200I)-NanoLuc® Fusion Vector

MET(M1250T)-NanoLuc® Fusion Vector

MET(P991S)-NanoLuc® Fusion Vector

MET(T1173I)-NanoLuc® Fusion Vector

MET(T992I)-NanoLuc® Fusion Vector

MET(V1092I)-NanoLuc® Fusion Vector

MET(Y1230A)-NanoLuc® Fusion Vector

MET(Y1230C)-NanoLuc® Fusion Vector

MET(Y1230D)-NanoLuc® Fusion Vector

MET(Y1230H)-NanoLuc® Fusion Vector

MET(Y1235D)-NanoLuc® Fusion Vector

NanoBRET^®Target Engagement K192 Kinase Selectivity System

NanoBRET^®Target Engagement CDK Selectivity Systems

CDK10-NanoLuc^® Fusion Vector

CDK14-NanoLuc^® Fusion Vector

CDK16-NanoLuc^® Fusion Vector

CDK17-NanoLuc^® Fusion Vector

CDK18-NanoLuc^® Fusion Vector

CDK1-NanoLuc^® Fusion Vector

CDK2-NanoLuc^® Fusion Vector

CDK3-NanoLuc^® Fusion Vector

CHEK2-NanoLuc^® Fusion Vector

CSNK2A1-NanoLuc^® Fusion Vector

DCLK3-NanoLuc^® Fusion Vector

DDR2(N456S)-NanoLuc^® Fusion Vector

DYRK2-NanoLuc^® Fusion Vector

EPHA3-NanoLuc^® Fusion Vector

EPHB1-NanoLuc^® Fusion Vector

ERN2-NanoLuc^® Fusion Vector

FES-NanoLuc^® Fusion Vector

FGFR3(G697C)-NanoLuc^® Fusion Vector

FLT1-NanoLuc^® Fusion Vector

FLT3(D835H)-NanoLuc^® Fusion Vector

FLT3(D835V)-NanoLuc^® Fusion Vector

FLT3(D835Y)-NanoLuc^® Fusion Vector

FLT3(K663Q)-NanoLuc^® Fusion Vector

FLT3(N841I)-NanoLuc^® Fusion Vector

FLT3(R834Q)-NanoLuc^® Fusion Vector

FYN(Y531F)-NanoLuc^® Fusion Vector

HCK-NanoLuc^® Fusion Vector

IGF1R-NanoLuc^® Fusion Vector

INSR-NanoLuc^® Fusion Vector

Intracellular TE Nano-Glo^® Substrate/Inhibitor

JAK2(V617F)-NanoLuc^® Fusion Vector

JAK2-NanoLuc^® Fusion Vector

KIT(A829P)-NanoLuc^® Fusion Vector

KIT(D816H)-NanoLuc^® Fusion Vector

KIT(D816V)-NanoLuc^® Fusion Vector

KIT(L576P)-NanoLuc^® Fusion Vector

KIT(V559D)-NanoLuc^® Fusion Vector

KIT(V559D,T670I)-NanoLuc^® Fusion Vector

KIT(V559D,V654A)-NanoLuc^® Fusion Vector

LIMK1-NanoLuc^® Fusion Vector

LRRK2(G2019S)-NanoLuc^® Fusion Vector

LRRK2(I2020T)-NanoLuc^® Fusion Vector

LRRK2(R1441C)-NanoLuc^® Fusion Vector

LRRK2-NanoLuc^® Fusion Vector

MAP2K6-NanoLuc^® Fusion Vector

MAP3K19-NanoLuc^® Fusion Vector

MAP3K2-NanoLuc^® Fusion Vector

MAP3K3-NanoLuc^® Fusion Vector

MAP4K5-NanoLuc^® Fusion Vector

MAPK14(T106M)-NanoLuc^® Fusion Vector

MERTK(A708S)-NanoLuc^® Fusion Vector

MERTK-NanoLuc^® Fusion Vector

MET(D1228H)-NanoLuc^® Fusion Vector

MET(D1228N)-NanoLuc^® Fusion Vector

MET(F1200I)-NanoLuc^® Fusion Vector

MET(M1250T)-NanoLuc^® Fusion Vector

MET(P991S)-NanoLuc^® Fusion Vector

MET(T1173I)-NanoLuc^® Fusion Vector

MET(T992I)-NanoLuc^® Fusion Vector

MET(V1092I)-NanoLuc^® Fusion Vector

MET(Y1230A)-NanoLuc^® Fusion Vector

MET(Y1230C)-NanoLuc^® Fusion Vector

MET(Y1230D)-NanoLuc^® Fusion Vector

MET(Y1230H)-NanoLuc^® Fusion Vector

MET(Y1235D)-NanoLuc^® Fusion Vector

MYLK3-NanoLuc^® Fusion Vector

MYLK4-NanoLuc^® Fusion Vector

NanoLuc^®-ABL1(E255K) Fusion Vector

NanoLuc^®-ABL1(F317I) Fusion Vector

NanoLuc^®-ABL1(F317L) Fusion Vector

NanoLuc^®-ABL1(H396P) Fusion Vector

NanoLuc^®-ABL1(M351T) Fusion Vector

NanoLuc^®-ABL1(Q252H) Fusion Vector

NanoLuc^®-ABL1(T315I) Fusion Vector

NanoLuc^®-ABL1(Y253F) Fusion Vector

NanoLuc^®-ABL2 Fusion Vector

NanoLuc^®-BLK Fusion Vector

NanoLuc^®-BRSK1 Fusion Vector