NanoBRET™ 590 Dyes

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Develop Novel NanoBRET™ Tracers to Enable Target Engagement Assays for New Targets


  • Leverage the same NanoBRET™-branded energy acceptors used to create most Promega NanoBRET™ tracers
  • Couple NanoBRET™ 590 SE Dyes to base compounds containing a reactive amine group
  • Create three unique tracer structures from a common starting material using the three linker variants of the NanoBRET™ 590 SE Dye
  • Synthesize tracers with an amine orthogonal coupling chemistry using Azide-Alkyne Click chemistry and the NanoBRET™ 590 Azide Dye
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